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Among 489 individuals, vitamin D status was categorized as likely deficient for 124 participants 25, likely sufficient for 287 59, and uncertain for 78 16. doxycycline vet canada In contrast, CTLA- 4 molecules mutated at Y182 showed a reduced ability to activate T cells when engaged with an inverse agonist compared to Y165F CTLA- 4, suggesting that this residue may also be important for the activating function of CTLA- 4 although less that the lysine- rich motif Figure 5E.
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